NGS of a 198 gene panel associated with pediatric tumors, sarcomas and haematological neoplasms. Complete genes: APC, ARID1A, ARID1B, ATRX, CDKN2A, CDKN2B, CEBPA, CHD7, CRLF1, DDX3X, DICER1, EBF1, EED, FAS, GATA1, GATA3, GNA13, ID3, IKZF1, KDM6A, MYOD1, NF1, NF2, PHF6, PRPS1, PTCH1, PTEN, RB1, SMARCA4, SMARCB1, SOCS2, SUFU, SUZ12, TET2, TP53, TSC1, TSC2, WT1, XIAP. Specific mutations : ACVR1, AKT1, ASXL1, ASXL2, CALR, CBL, CCND3, CCR5, CSF3R, CTNNB1, DAXX, DNMT3A, EP300, ERBB4, ESR1, EZH2, FASLG, FBXW7, GATA2, GNAQ, H3F3A, HDAC9, HIST1H3B, HRAS, IDH1, IDH2, IL7R, JAK1, JAK3, KDM4C, KDR, MAP2K1, MPL, MSH6, MTOR, NCOR2, NRAS, NT5C2, PIK3R1, PPM1D, PTPN11, RHOA, SETBP1, SETD2, SH2B3, SH2D1A, SMO, STAT3, STAT5B, TERT, TPMT, USP7, ZMYM3. Copy number variation : CDK6, GLI2, MDM2, MDM4. Relocations (translocations/fusions): BCL11B, BCOR, BCR, CAMTA1, DUSP22, ETV6, EWSR1, FOSB, FUS, GLIS2, HMGA2, KAT6A, KMT2A, KMT2B, KMT2C, LMO2, MAML2, MAN2B1, MECOM, MEF2B, MKL1, MLLT10, MN1, MYB, MYBL1, MYH11, MYH9, NCOA2, NCOR1, NOTCH2, NOTCH4, NR4A3, NTRK1, NTRK2, NTRK3, NUP214, NUP98, NUTM1, NUTM2B, PAX3, PAX7, PDGFB, PLAG1, RANBP17, RECK, RELA, ROS1, SS18, SSBP2, STAG2, STAT6, TAL1, TFE3, TP63, TSLP, TSPAN4, UBTF, USP6, YAP1, ZMYND11, ZNF384. Expression changes: BCL2, BCL6, TOP2A

Consult

Ref: LV4228 Categories: , , , Diseases: Solid tumorGenes: CREBBP, CRLF1, PAX7, ROS1, HDAC9, ARID1B, KMT2C, ERBB3, FGFR2, RHOA, FGFR3, TCF3, TP63, GLI2, EED, NT5C2, FGFR1, MLLT10, CIC, KAT6A, MECOM, FUS, ESR1, JAK2, ABL1, PDGFB, MYH9, EP300, STAG2, TSC2, MAN2B1, CDK6, MET, EZH2, KDM4C, GATA3, UBTF, FBXW7, WHSC1, CCND1, CBL, NUP98, GLI1, SH2B3, CCND3, DUSP22, PDGFRB, BCL6, ACVR1, ID3, ARID1A, MYB, NR4A3, DNMT3A, GNA13, SOCS2, PIK3CA, RECK, HIST1H3B, FOSB, GLIS2, ZNF384, NUP214, BCL11B, SMARCA4, KDR, SMO, MYOD1, USP6, TOP2A, MYH11, KRAS, NOTCH2, MYCN, PDGFRA, APC, LMO2, MDM2, PAX3, MYC, TPMT, YAP1, IDH1, ETV6, NCOA2, IGF1R, NTRK3, NCOR1, SS18, ERBB2, AKT1, ABL2, ASXL2, PIK3R1, SSBP2, TSLP, EGFR, KDM6A, ZMYM3, CDKN2B, NTRK2, NOTCH1, HMGA2, SETBP1, GNAQ, PHF6, BRAF, CCR5, FGFR4, TAL1, JAK1, H3F3A, EBF1, TSC1, RET, STAT6, KMT2D, CTNNB1, TET2, MAP2K1, MN1, PPM1D, ASXL1, CAMTA1, BCL2, RELA, HRAS, ERBB4, SUZ12, CALR, PTPN11, SETD2, PLAG1, IDH2, CSF1R, EWSR1, BCOR, MAML2, NUTM1, WT1, MYBL1, IKZF1, PTCH1, BCR, USP7, NUTM2B, PAX5, NCOR2, MKL1, MDM4, MTOR, RANBP17, CRLF2, MEF2B, TSPAN4, DDX3X, DAXX-2, NOTCH4-2, ZMYND11-2, GATA1-2, KMT2A-2, ATRX-2, TFE3-2, KMT2B-2, SH2D1A-2, CDKN2A-2, STAT3-2, FAS-2, CSF3R-2, CHD7-2, XIAP-2, STAT5B-2, NF1-2, MSH6-2, NTRK1-2, PRPS1-2, GATA2-2, KIT-2, PTEN-2, TP53-2, TERT-2, RAF1-2, CEBPA-2, FLT3-2, NPM1-2, RUNX1-2, ALK-2, CDK4-2, DICER1-2, MPL-2, NF2-2, RB1-2, SMARCB1-2, SUFU-2, FASLG-2, IL7R-2, JAK3-2, NRAS-2Delivery term: 35 days
sistemas genómicos
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